Levamisole-contaminated cocaine is an increasingly reported cause of a syndrome characterized by vasculitic skin lesions and immunologic abnormalities. With approximately 70% of cocaine in the United States now contaminated with levamisole, the incidence of this syndrome is likely to increase. TEK - Making crack cocaine with sodium bicarbonate (baking soda) methods Cocaine & Crack Home Wiki Studies Forum Groups Blog Video Images News Chat Drugs Forum DRUG-FORUMS Cocaine & Crack TEK. The amount of levamisole found in cocaine is typically not that large, so it's not to add weight, and it's neither a stimulant nor a local anesthetic. Cocaine anca vasculitis. Levamisole is a known immunomodulating agent frequently used as a cutting agent in cocaine consumed in the United States today. Numerous cases of anti-neutrophil cytoplasmic antibody (ANCA) vasculitis connected with the use of levamisole-adulterated cocaine have previously been reported in the literature, classically characterized by a retiform purpuric rash. Levamisole has become a common additive to illicit cocaine. It is thought to intensify the “high” by releasing dopamine in the brain, acts as a bulking agent, and is a difficult adulterant to recognize. Potential risks of levamisole-laced cocaine include neutropenia, agranulocytosis, arthralgias, retiform purpura, skin necrosis, and fever. The patient in this video presented to the emergency department with severe pain secondary to ear and nose vasculitis caused by the use of levamisole adulterated cocaine.

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